Excerpt from General Medicine The vaccine should be injected in the smallest quan ity capable of provoking a beneficial reaction. Large doses tend to diminish the resisting power and to favor the extension of the disease. A second dose of vaccine must not be introduced until the negative phase of the reaction has passed. Disregard of this precaution tends to prolong a condition of lowered resistance. The deter mination of the point at which the negative phase has terminated and a second injection can be given is made by the opsonic index. Some authors, however, depend on clinical indications, as derived from the existence or non-existence of fever, the. General condition of the patient, and the state of the local infection. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.