COX-2 Blockade in Cancer Prevention and Therapy

Name: COX-2 Blockade in Cancer Prevention and Therapy
SKU: 9986140
Price: 327.00 NZD
Availability: InStock

Format:

Paperback / softback

Series:

Cancer Drug Discovery and Development

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Description

This book chronicles the evidence for the chemopreventive and therapeutic effects of cyclooxygenase-2 (COX-2) inhibitors against virtually all forms of cancer and presents exciting new opportunities for the use of COX-2 blockade in its prevention and treatment. The authors elucidate the process by which COX-2 inhibitors interrupt prostaglandin biosynthesis and cancer development, examine the positive epidemiological effects of such NSAIDs as aspirin and ibuprofen on various cancers, and demonstrate through animal models that COX-2 inhibitors and NSAIDs inhibit a variety of malignant neoplasms in vivo. They also present genetic models confirming the critical role of COX-2 in carcinogenesis and discuss how its molecular biology modulates carcinogenesis. In addition, the authors review the clinical applications of selected NSAIDs that are immediately relevant to cancer prevention and control and outline the future prospects of COX-2 blocking agents.

Release date NZ

November 19th, 2010

Audience

Professional & Vocational

Contributor

Edited by Randall E. Harris

Edition

Softcover reprint of the original 1st ed. 2003

Illustrations

X, 371 p.

Pages

371

Series

Cancer Drug Discovery and Development

Dimensions

178x254x20

ISBN-13

9781617373046

Product ID

9986140

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COX-2 Blockade in Cancer Prevention and Therapy

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