Written by a team of international researchers and teachers at the cutting edge of chemical biology research, this book provides an exciting, comprehensive introduction to a wide range of chemical and physical techniques with applications in areas as diverse as molecular biology, signal transduction, drug discovery and medicine. Techniques include: Cryo-electron microscopy, atomic force microscopy, differential scanning calorimetry in the study of lipid structures, membrane potentials and membrane probes, identification and quantification of lipids using mass spectroscopy, liquid state NMR, solid state NMR in biomembranes, molecular dynamics, two dimensional infra-red studies of biomolecules, single and two-photon fluorescence, optical tweezers, PET imaging and chemical genetics. KEY FEATURES: * a unique guide to the rapidly evolving, interdisciplinary field of chemical biology. * adopts a molecular structure for maximum flexibility. * addresses relevant, topical chemical biological questions throughout. * includes stunning illustrations. * associates website with PowerPoint slides of figures within the book.
Chemical Biology: Techniques and Applications provides an invaluable resource for final year undergraduate and post graduate bioscience and biomedical students and pharmaceutical researchers with an interest in this fascinating, and ever changing field.
Dr Larijani, London, UK.Research scientist, Cell Biophysics Laboratory, London Research Institute, Cancer Research UK, London WC2A 3PX Dr. Rudiger Woscholski, London, UK.Lecturer, Biochemistry Building, Imperial College, South Kensington, London SW7 2AY, UK Dr. Colin A. Rosser, Oxford, UK.Director of Studies, St Anthony School, Rye St Anthony, Headington, Oxford OX3 0BY, UK