Piraro discusses his own life, from a poor religious upbringing to life with a well-paid job in New York, leading up to his present fulfilling life as a cartoonist. The award winning Bizarro is an edgier, more inventive version of The Far Side, with every panel taking on original characters and themes. The book also discusses Piraro's strong feelings about animal rights and politics, both of which are the favoured topics of his paintings and one-man comedy show.
Piraro was born in Kansas City and grew up in Tulsa before living in Dallas for many years. He currently lives in Brooklyn and has a strong fan base in San Francisco. The cartoon runs daily in almost 200 markets across the country and in Canada.