Non-Fiction Books:

BCL-2 Family Proteins

Methods and Protocols
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Hardback
$568.00
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Description

This volume explores numerous techniques for the genetic, molecular, biochemical, and structural examination of BCL-2 family proteins and their interactions. The chapters in this book cover topics such as the relevance of BCL-2 proteins in health and disease; evaluating cellular dependencies to specific BCL-2 family proteins; flow-cytometry-based methods for measuring BCL-2 proteins and mitochondrial-based cell death; measuring activity and  interactions of BCL-2 family proteins in the presence of mitochondria, artificial membranes or yeast; conformational activation and oligomerization of pro-apoptotic proteins BAX and BAK leading to cytochrome c release and apoptosis; structural and biophysical studies in solution and lipid vesicles using nuclear magnetic resonance, cryo-electron microscopy, fluorescence microscopy and electron paramagnetic resonance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, BCL-2 Family Proteins: Methods and Protocols is a valuable resource to inspire and encourage novice and established scientists to further their research and make new discoveries in this exciting field.
Release date NZ
December 7th, 2018
Audience
  • Professional & Vocational
Contributor
  • Edited by Evripidis Gavathiotis
Edition
1st ed. 2019
Illustrations
66 Illustrations, color; 30 Illustrations, black and white; XI, 360 p. 96 illus., 66 illus. in color.
Pages
360
ISBN-13
9781493988600
Product ID
28271524

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