During the late 1970s, hundreds of cases were studied at The Atticus Institute, a small psychology lab founded by Dr. Henry West. Dr. West and his fellow researchers were introduced to an unusual middle-age woman whose supernatural abilities tested far beyond any subject they had ever before witnessed. This was, and to this day remains, the only government-confirmed case of possession.

After researchers at a parapsychology lab realize their newest test subject is possessed by an evil entity, the U.S. Government intervenes and subsequently takes total control. The research institute's fou­nder, Dr. Henry West, and his team soon uncover that the government's in­tention is to weaponise the demon and make use, for military purposes, its uncanny powers.